The experimental protocols followed were in accordance with the NIH guidelines and approved by the … This particular colony was selected because of a low incidence of hydronephrosis. Pharmaco-molecular assessment of the effects of anandamide and its antagonists on hippocampal tissue in Wistar albino rats. The wistar albino rats were housed in groups of four polycarbonate cages. Wistar rat is another common hybrid albino model animal. The experimental animals were divided into six weight matched groups. Effects and formulation of silver nanoscaffolds on cytotoxicity dependent ion release kinetics towards enhanced excision wound healing patterns in Wistar albino rats L. Sethuram, J. Thomas, A. Mukherjee and N. Chandrasekaran, RSC Adv. Group A (n=10) was the control group while group B (n=40) was the experimental group. The first group containing 6 rats was assigned as a control group. aqueous leaf extract (CALE) on lipid profile and hematological changes induced by exposure to low-dose heavy metal mixture in male albino rats. Group A Iran J Basic Med Sci, Vol. Finally they were cleared in 4% KOH and stored in glycerin. In order to evaluate the protective effects of Corchorus olitorius leaves, twenty Wistar albino rats were divided into four different groups. Twenty albino wistar rats were randomly divided into four experimental groups of five rats each, Control group were fed normal rat feed with distilled water, Group 2,3 and 4 were fed normal rat feed, water and received daily oral administration of lead acetate 250mg/kg daily. Nutritional ketosis has been proven effective for seizure disorders and other neurological disorders. The extract administration was in two phases. Pharm. We tested exogenous ketone supplements added to food and fed chronically for 83 days in SPD rats … The focus of this study was to determine the effects of ketone supplementation on anxiety-related behavior in Sprague-Dawley (SPD) and Wistar Albino Glaxo/Rijswijk (WAG/Rij) rats. Wistar rats: ( wis'tehr ), an inbred strain of rats, homozygous at most loci, produced by strict brother-sister inbreeding over many generations to develop animals for research with the same general genetic composition. It has the distinct honor of being the first rat stock developed to serve as a model animal. Animal Grouping: The study was performed on twenty-four (24) wistar-rmale albino rats housed in ventilated cages and grouped into four of six rats each. The normal (group 1) and toxic (group 2) controls received deionized water and metal … Male and female wistar albino rats weighing 150-180 grams, were obtained from the animal house of Sainath Agen-cies, Hyderabad (282/PO/Bt/S/2000 CPCSEA). Behavioral changes, signs of … Animal study was performed according to the following process: 50 male Albino Wistar rats, weighing 100-120 grams, after 10 days of acclimatization, the rats were randomly divided into two main groups. Groups B, C and D were administered 30mg/kg body weight potassium bromate. They were accomodatedin polypropylene cages with standard diet and water ad libitum. Male Wistar albino rats (200–250g) were purchased at Albino Research Center, Bachupally, Hyderabad. They were maintained on a 12-h light-dark cycle in a temperature-controlled (22°C) colony room and had free access to food and water. However, B administration reversed BPA-induced alterations in rat tissues in a dose-dependent manner. Transferred to Charles River UK in 1996. Outbred Rats - Hsd:WI - 001. Experiment was designed as per ethical norms of CPCESA and IAEC Malla Reddy Institute of Pharmaceutical Sciences (1662/PO/a/12/ CPCSEA). Animal‐rearing facility conditions were optimized for the light–dark cycle, that is, twelve‐hour … Serum testosterone levels were measured at the baseline and at the … Eur Rev Med Pharmacol Sci Year: 2020 Vol. Wistar rats encompass a number of rat substrains that have been derived from a common lineage over the past 50+ years. (20) male albino rats of Wistar (150-195 g) were used in the present study. A. Madhuri *, S. Qairunnisa, M. Suresh, K. Ambareesha Kondam and M. Chandrasekhar. A total of 34 male Albino rats [Wistar strain], 2 months of age, weighing 150-160 gm were used for the experiment. They were provided with food and water ad libitum. The number of spike-wave discharges (SWDs) was gradually elevated from the 19th pregnancy day to delivery. Group A served as the control. The animals were housed in cages kept in an adequate animal house environment at the Madonna University, Elele, Nigeria. An authoritative source for the science and technological discoveries that matter for the general public. Behav. The outbred Wistar and Wistar HAN strains have been used widely in Europe for … The average weight of randomly selected male rats was in the range between 120 and 130 g in all groups. Groups 3-11 were treated with ELEIG with or without SA. Group 1 (control) was given feed and water ad libitum. The experiments . ABSTRACT: Introduction: Global warming is one of the major issues in the … •The Wistar bloodline has contributed more strains of rats than any other line. Wistar Han IGS Rat Details. ANTIOXIDANT CHANGES IN WISTAR ALBINO RATS AFTER ACUTE HEAT STRESS. Twenty male albino Wistar rats were procured from the laboratory animal‐rearing facility of the faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan. The substrains of Wistar rats: Wistar Hannover (Han/Wistart) and Wistar Unilever (WU) rat are outbred; while Wistar Kyoto and Wistar Furth are inbred strains. Res., 2015, 7(8):729-734 _____ 731 were performed according to the Guide for the care and use of laboratory … B. Description Price Currency; 50-74g weight, 21-26 approx days: 28.25: USD: 75-99g weight, 27-30 approx days Twenty female Wistar albino rats, weighing between 160 and 170 g were collected from animal house of Jahangirnagar University, Dhaka and were allowed free access to laboratory rodent diet and water ad-libitum throughout the experimental period. There are various routes of drug administration in rats like 1) Intraoeritoneal 2) Intravenous3) Intramuscular 4) Subcutaneous 5) Intracardiac etc. During the experimental study rats were fed with … of rats in the USA. These animals were killed by deep ether anaesthesia and fixed in 80% alcohol. Rederived by GlaxoWellcome from Han Wistar stock supplied by BRL. The rats were inflicted with excision wounds as … Citation: Kovács Z, D'Agostino DP and Ari C (2018) Anxiolytic Effect of Exogenous Ketone Supplementation Is Abolished by Adenosine A1 Receptor Inhibition in Wistar Albino Glaxo/Rijswijk Rats. Address for correspondenceCamila Albuquerque Melo de Carvalho, PhD, Centro Universitário Barão de Mauá, Rua Ramos de Azevedo, 423, Ribeirão Preto, SP, 14090 … 24 - N. 22 Pages: 11871-11882 DOI: 10.26355/eurrev_202011_23845. To Scientific Products Farm, Ltd. [predecessor of Charles River United Kingdom (CRUK)] in 1947 from Wistar Institute. The present work investigated the protective effects of Costus afer Ker Gawl. The animals were allowed to acclimatize for seven days before the commencement of administration. 3.3.03) Animal House of PRIST University, Thanjavur. Serum … Comparing albino and hooded Wistar rats of both sexes on a range of behavioral and learning tasks R. A. BOAKES, B. This video describes the standard method of collection of blood from retro orbital plexus in wistar albino rats. Figure 6. 1, Jan 2013 29 Zahra Bathaie et al Saffron … He later established Wistar Institute in Philadelphia that will have a major role in the development of the rat as an important laboratory animal similar to the impact the Jackson laboratory had on the development of the laboratory mouse. In phase one, doses of 10, 100 and 1000 mg/kg body weight of rats was administered while in phase two, 1500, 3000 and 5000mg/kg body weight of rats was orally administered. They were adequately fed with normal rat chow … Keywords: exogenous ketone supplement, ketosis, anxiety, EPM, adenosine, WAG/Rij rats. Methods: Ciprofloxacin was administered to newly born Wistar albino rat pups at a dose of 20 mg/kg body weight intraperitoneally twice daily from day-1 to day-14 after birth. Neurosci. Extraction . Fresh leaves were shade … The Wistar rat, Wistar Hannover (Wistar HAN) rat, and Wistar Unilever (WU) rat are outbred rat strains, while the Wistar Kyoto and Wistar Furth rats are inbred strains. Lobund-Wistar rat… Wistar albino rats (male), weighing 150 ± 10 g, used for the study, were housed in cage individually under controlled conditions of 12 h light/12 h dark cycle and at a temperature of 22 ± 2°C, with free access to rat/mice feed (Lipton, India) and water ad libitum. Meanwhile, the characteristics of individual SWDs did not change suggesting that SWD … In addition, groups 3 and 4 received 100mg/kg and 150mg/kg oral administration of vitamin C … CARVER University of Sydney, Sydney, Australia Albino and hooded WlStar rats of both sexes were compared on several behavioral measures and learning tasks. Treatment was done orally and lasted for 14 days. Overall the most marked behavioral differences produced by … In order to establish the safety use of TR-Y017, this study aims to evaluate the effects of its acute and sub-acute oral administration to Wistar albino rats. … BOOT, J. V. CLARKE, and A. Our institutional and national guidelines were followed for the care and use of laboratory animals throughout the experiment. This has markedly diluted the original strain. 16, No. The animals were housed with free access to food and water for one week in an air-conditioned room (250C) under a 12 hr light: dark cycle prior to the experiment. 12:29. doi: 10.3389/fnbeh.2018.00029 IGS refers to animals bred using the Charles River International Genetic Standardization (IGS) Program. Department of Physiology, Meenakshi Medical College & Research Institute, Enathur, Kanchipuram - 631552, Tamil Nadu, India. Methods: Acute oral toxicity tests were performed on Wistar rats by oral forcefeeding with a single dose of 2000 mg/kg in accordance with the Organization for Economic Co-operation and Development (OECD) Guidelines and … [ Wistar Institute] Front. Sprague-Dawley rats were derived from Wistar rat. Group 2 was exposed to SA at a dose of 4.1 mg/kg body weight (kgbw) for two weeks. Group 2 and 3 received 0.5 ml of a concoction of Andrographis paniculata and Nilavembu kudineer (a concoction of 9 herbs) respectively for 30 days. Being the first rat stock developed to serve as a control group while group B ( )... Han Wistar stock supplied by BRL rat substrains that have been derived from a common lineage over the past years... Alcian blue 4.1 mg/kg body weight potassium bromate laboratory conditions of 12-hour light-dark before. The experiment low-dose heavy metal mixture in male albino rats AFTER ACUTE HEAT.. The major issues in the present work investigated the protective effects of and. 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